Even though I have wxGTK installed, eselect-wxwidgets does not detect it with a 17.1 profile: $ eselect wxwidgets list Available wxWidgets profiles: (none found) As a result wx-config is broken and I cannot build any wxWidgets apps.
The fix seems to be changing: WXCONFDIR="${EROOT}"/usr/lib/wx/config to: WXCONFDIR="${EROOT}"/usr/lib64/wx/config at the top of /usr/share/eselect/modules/wxwidgets.eselect I'd submit a patch but I couldn't figure out how to do it properly for multilib.
Patch is available in bug 552500 *** This bug has been marked as a duplicate of bug 552500 ***