Latest libxml2 is in version 2.9.12 witch causes dependency conflict RDEPEND=" <dev-libs/libxml2-2.9.12 >=dev-libs/libxslt-1.1.28" Maybe there should be <=dev-libs/libxml2-2.9.12. WARNING: One or more updates/rebuilds have been skipped due to a dependency conflict: dev-libs/libxml2:2 (dev-libs/libxml2-2.9.12:2/2::gentoo, ebuild scheduled for merge) USE="ipv6 python readline -debug -examples -icu -lzma -static-libs -test -verify-sig" ABI_X86="32 (64) (-x32)" PYTHON_TARGETS="python3_8 -python3_7 -python3_9" conflicts with <dev-libs/libxml2-2.9.12 required by (dev-python/lxml-4.6.3:0/0::gentoo, installed) USE="threads -doc -examples -test" ABI_X86="(64)" PYTHON_TARGETS="python3_8 (-pypy3) (-python3_10) -python3_7 -python3_9" ^ ^^^^^^
*** This bug has been marked as a duplicate of bug 790737 ***