Created attachment 669797 [details, diff]
After upgrading to systemd-246 some time ago, I discovered that after resuming from suspend-to-ram, there was no internet connection (I'm using systemd-networkd). Restarting the systemd-networkd service brings the interface up again. This is a upstream bug (https://github.com/systemd/systemd/issues/16696) and I manually included a user patch from the PR at https://github.com/systemd/systemd/pull/16697 and works for me.
I've attached the patch here. It would be nice to be included in portage, until a newer version of systemd is released.