The file /etc/modprobe.d/alsa.conf (which is installed from /usr/portage/media-sound/alsa-utils/files/alsa-modules.conf-rc) contains the following comment:
## You need to customise this section for your specific sound card(s)
## and then run `update-modules' command.
As far as I understand, update-modules no longer exists, and it is no longer necessary to run any commands after editing the file.
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