This package still uses ruby 2.2. Upstream is no longer supporting Ruby 2.2 and security support ends on March 1st, 2018. Ruby 2.2 will be masked for removal on or shortly after this date, along with any packages still depending on ruby22. Please update your package to use a newer ruby slot. Use ruby 2.3 if you can only use one slot and your package is in arch Use ruby 2.4 if you can only use one slot and your package is in ~arch Use as many ruby targets as possible when you can use multiple slots.
bioruby-1.4.3.0001-r1 does install or work at all with all current ruby implementations. I have marked bioruby 1.5.1 stable and removed the broken version.