Just reinstalled sandbox-0.2.2, and tried to remerge python-2.2-r1.ebuild. It caught the following violation: unlink: /usr/share/man/man1/python.1 Didn't have sanbox installe during my previous testing so I didn't see this.
-r2 now exists. Changed ./configure --manpath=/usr/share/man to ./configure --manpath='${prefix}'/share/man.