I'm thinking this should be possible if we make the bundled packages themselves (i.e. pip, setuptools, wheel) build and install their own wheels.
The bug has been closed via the following commit(s): https://gitweb.gentoo.org/repo/gentoo.git/commit/?id=45ad79bd0148f4e7f70d2f1b94512f10aa2d4c87 commit 45ad79bd0148f4e7f70d2f1b94512f10aa2d4c87 Author: Michał Górny <mgorny@gentoo.org> AuthorDate: 2024-06-22 12:39:09 +0000 Commit: Michał Górny <mgorny@gentoo.org> CommitDate: 2024-06-22 12:43:26 +0000 dev-python/virtualenv: Use ensurepip instead of bundled wheels Closes: https://bugs.gentoo.org/807643 Signed-off-by: Michał Górny <mgorny@gentoo.org> .../files/virtualenv-20.26.3-ensurepip.patch | 37 +++++++ dev-python/virtualenv/virtualenv-20.26.3-r2.ebuild | 118 +++++++++++++++++++++ 2 files changed, 155 insertions(+)