iio-sensor-proxy can be built without systemd by simply commenting out the systemd dependency in meson.build and supplying an appropriate initscript. Void Linux does this, for example. It just works as expected. It would be worth letting non-systemd users install iio-sensor-proxy from GURU rather than having to do the above manually.
I've committed an update based on a forum post I found: https://forums.gentoo.org/viewtopic-t-1115254-start-0.html Commit: https://gitweb.gentoo.org/repo/proj/guru.git/commit/?h=dev&id=b3679440310877c861685630fb986c35e2171653 This is my first contribution, so I'd be happy to receive feedback.