Contrary to the description of the "tsr" USE-flag, net-misc/etherdfs does NOT build the TSR program, but seems to download and install a pre-built ETHERDFS.EXE file. Please fix the ebuild to actually compile the program from source. Thanks!
Sorry, I don't see any way to achieve this here. Yes, I agree, the metadata.xml description is not correct and I will adjust it. But based on the makefile of the tsr source, it uses windows only stuff, like "wasm" or "wcl". The options used for "wasm" do not match "nasm" and "wcl" is Watcom. Open Watcom may work, I don't know, but it's not packaged in Gentoo. If you have patches or other steps how to compile this in linux, feel free to submit a PR or more information here.