Attempting to emerge mythtv with use=perl resulted in this warning during configure: WARNING: disabling Perl bindings; missing XML::Simple and no perl bindings. I added XML-Simple to the deps for use=perl and it worked.
Please attach a full log of your failure. While it may be that adding a dependency fixed your problem, the real reason for the dependency may be deeper nested.
Also, emerge --info for mythtv would be helpful. Currently I can only assume you're building with USE="-xmltv", as USE="xmltv" could unintentionally hide this problem :)
https://wiki.gentoo.org/wiki/Attach_the_logs_to_the_bug_ticket We need to have all information at hand before ticket assignment, so that the maintainer can look after it in one session with minimal number of callbacks. Please reopen this ticket (Status:unconfirmed) afterwards.