These dependencies are missing from app-emulation/virt-manager-0.9.0-r1: app-emulation/libvirt[python] net-misc/spice-gtk Missing "app-emulation/libvirt[python]" now that python has been removed from the system profile. net-misc/spice-gtk is needed if you want to use Spice. The Fedora Project resolved this issue by making spice-gtk a hard dependency: https://bugzilla.redhat.com/show_bug.cgi?id=697729 I imagine that we could have a USE flag for this, but it doesn't make much sense to do that because virt-manager is meant to control remote machines and whether or not they have spice support is not something we can control at the local machine.
net-misc/spice-gtk needs to be net-misc/spice-gtk[python] Furthermore, turning this on triggers bug #377051. We can fix this independently of that, but I will post in that bug explaining that the python USE flag triggers it.
This is already fixed.