Whenever spice-gtk is build with gtk3 and python use flag, python module is missing. Without gtk3 use flag, following file exists: /usr/lib64/python2.7/site-packages/SpiceClientGtk.so
See configure.ac. The short story: no pygtk planned for 3.x, you're supposed to use gtk via pygobject (using gobject-introspection), so python module disabled.