Dear colleagues, We are pleased to announce that OASIS version 4.0 is now available. This version includes an improved SAD-phasing algorithm and a GUI for controlling and monitoring Dual-space iteration processes, which involve phasing, density-modification and model-building programs. More details at http://cryst.iphy.ac.cn/Project/protein/protein-R.html Download at http://cryst.iphy.ac.cn/Download/download.html Hai-fu Fan Research group on methods of solving crystal structures Institute of Physics, CAS, China URL: http://cryst.iphy.ac.cn