pyserial ebuild doesn't set RDEPEND, so the current RDEPEND=$DEPEND means that unzip can't be uninstalled(well not without it being pulled in next time you emerge world :P). Thanks, James Reproducible: Always
Created attachment 191000 [details, diff] pyserial-set_rdepend.patch
Fixed. pyserial-2.4 uses .tar.gz tarball, so it doesn't need unzip at all.