[This is mostly a reminder for myself for once I'm ready to get back to work on bugs] The iscsitarget ebuild installs the iscsi_trgt.ko kernel module under the kernel/* directory. This means that it will be deleted after any make modules_install. As when running such a modules_install you usually are not changing kernel options, this should be avoided, as it requires iscsitarget to be re-emerged many times when configuring a system.
Okay, fixed.