in the current state, wine has problems with nvidia drivers when initializing certain videomodes, which needs a little workaround. Also, many games need a certain fix for DirectInput's mouse handler. Without the fix, the mouse cursor will always stick to the center of the screen. I have added a VIDEO_CARDS=nvidia option and a USE=mousehack flag to the wine ebuild so users can easily surround both problems without having to compile the source by hand or write their own ebuilds on a side note, the mousehack does absolutely nothing unless you manually activate it, so the use flag could be left out, always applying the patch, which is to be decided before checking this in
Created attachment 95099 [details, diff] mousehack diff file
Created attachment 95100 [details, diff] nvidia-specific fix for D3D videomode switching
Created attachment 95101 [details, diff] ebuild diff with useflags for both patches
sorry, but we dont have man power to maintain such things in Gentoo please get the issues integrated upstream and we'll just pull from there