diff -ur wxPython-4.0.7.post2/etg/region.py wxPython-4.0.7.post2-patched/etg/region.py
--- wxPython-4.0.7.post2/etg/region.py	2019-11-11 19:54:31.000000000 -0700
+++ wxPython-4.0.7.post2-patched/etg/region.py	2022-08-09 12:27:58.196518224 -0600
@@ -88,11 +88,12 @@
     c.mustHaveApp()
     c.find('operator++').ignore()
 
-    # SIP maps operator bool() to __int__, but Classic used __nonzero__. Does
-    # it make any difference either way?
     c.find('operator bool').ignore()
     c.addCppMethod('int', '__nonzero__', '()', 'return (int)self->operator bool();',
                    'Returns true while there are still rectangles available in the iteration.')
+    c.addCppMethod('int', '__bool__', '()', 'return (int)self->operator bool();',
+                   'Returns true while there are still rectangles available in the iteration.')
+
 
     c.addCppMethod('void', 'Next', '()', 'self->operator++();',
                    'Move the iterator to the next rectangle in the region.')
diff -ur wxPython-4.0.7.post2/etg/windowid.py wxPython-4.0.7.post2-patched/etg/windowid.py
--- wxPython-4.0.7.post2/etg/windowid.py	2019-11-11 19:54:31.000000000 -0700
+++ wxPython-4.0.7.post2-patched/etg/windowid.py	2022-08-09 12:31:47.557488273 -0600
@@ -53,12 +53,12 @@
                 MethodDef(name='wxWindowIDRef', className='wxWindowIDRef', isCtor=True,
                     briefDoc='Create reference from an ID',
                     items=[ ParamDef(type='int', name='id') ]),
-                
+
                 MethodDef(name='wxWindowIDRef', className='wxWindowIDRef', isCtor=True,
                     briefDoc='Copy an ID reference',
                     items=[ ParamDef(type='const wxWindowIDRef&', name='idref') ]),
                 ]),
-            
+
             MethodDef(name='~wxWindowIDRef', className='wxWindowIDRef', isDtor=True),
 
             MethodDef(type='int', name='GetValue',
@@ -73,11 +73,13 @@
             """)
 
     klass.addCppMethod('int', '__int__', '()',
-        doc="Alias for GetValue allowing the IDRef to be passed as the WindowID parameter when creating widgets or etc.",
-        body="""\
-            return self->GetValue();
-            """)
-    
+        doc="Alias for GetValue allowing the IDRef to be passed as the WindowID parameter when creating widgets or other places an integer type is needed.",
+        body="return self->GetValue();")
+    klass.addCppMethod('int', '__index__', '()',
+        doc="See :meth:`__int__`",
+        body="return self->GetValue();")
+
+
     klass.addCppMethod('bool', '__eq__', '(wxWindowID id)', "return self->GetValue() == id;")
     klass.addCppMethod('bool', '__ne__', '(wxWindowID id)', "return self->GetValue() != id;")
     klass.addCppMethod('bool', '__lt__', '(wxWindowID id)', "return self->GetValue() < id;")
@@ -92,17 +94,17 @@
     # and finish it up by adding it to the module
     module.addItem(klass)
 
-    # Now, let's add a new Python function to the global scope that reserves an 
-    # ID (or range) and returns a ref object for it. 
-    module.addPyFunction('NewIdRef', '(count=1)', 
+    # Now, let's add a new Python function to the global scope that reserves an
+    # ID (or range) and returns a ref object for it.
+    module.addPyFunction('NewIdRef', '(count=1)',
         doc="""\
-            Reserves a new Window ID (or range of WindowIDs) and returns a 
-            :class:`wx.WindowIDRef` object (or list of them) that will help 
+            Reserves a new Window ID (or range of WindowIDs) and returns a
+            :class:`wx.WindowIDRef` object (or list of them) that will help
             manage the reservation of that ID.
 
-            This function is intended to be a drop-in replacement of the old 
-            and deprecated :func:`wx.NewId` function, with the added benefit 
-            that the ID should never conflict with an in-use ID or other IDs 
+            This function is intended to be a drop-in replacement of the old
+            and deprecated :func:`wx.NewId` function, with the added benefit
+            that the ID should never conflict with an in-use ID or other IDs
             generated by this function.
             """,
         body="""\
diff -ur wxPython-4.0.7.post2/unittests/test_windowid.py wxPython-4.0.7.post2-patched/unittests/test_windowid.py
--- wxPython-4.0.7.post2/unittests/test_windowid.py	2022-08-09 12:26:19.466530951 -0600
+++ wxPython-4.0.7.post2-patched/unittests/test_windowid.py	2022-08-09 12:32:45.293480641 -0600
@@ -75,6 +75,7 @@
         val = ref1 <= ref2
         assert type(val) == bool
 
+
     def test_WindowIDRef02(self):
         d = {wx.NewIdRef(): 'one',
              wx.NewIdRef(): 'two'}
@@ -82,6 +83,24 @@
         for k in keys:
             val = d[k]
 
+
+    def test_WindowIDRef03(self):
+        # Ensure wx.WindowIDRef can be converted to int without warning when
+        # making a call to warrped method. In Py3.8+ this means there needs to
+        # be an __index__ method.
+
+        # Turn warnings into exceptions so this test will fail if there is
+        # a warning
+        import warnings
+        warnings.simplefilter('error')
+
+        wid = wx.NewIdRef()
+        assert isinstance(wid, wx.WindowIDRef)
+
+        b = wx.Button(self.frame, wid, 'button')
+        assert b.GetId() == wid.GetId()
+
+
 #---------------------------------------------------------------------------