diff --git c/config/cmake_files/medMacros.cmake w/config/cmake_files/medMacros.cmake
index b79f387..7c82cec 100644
--- c/config/cmake_files/medMacros.cmake
+++ w/config/cmake_files/medMacros.cmake
@@ -398,7 +398,7 @@ MACRO(MED_FIND_HDF5)
     ##
     ## Requires 1.10.x version
     ##
-    IF (NOT HDF_VERSION_MAJOR_REF EQUAL 1 OR NOT HDF_VERSION_MINOR_REF EQUAL 10 OR NOT HDF_VERSION_RELEASE_REF GREATER 1)
+    IF (HDF5_VERSION VERSION_LESS 1.10.2)
         MESSAGE(FATAL_ERROR "HDF5 version is ${HDF_VERSION_REF}. Only versions >= 1.10.2 are supported.")
     ENDIF()
     ##
diff --git c/src/ci/MEDfileCompatibility.c w/src/ci/MEDfileCompatibility.c
index b5c42d1..d94e6a8 100644
--- c/src/ci/MEDfileCompatibility.c
+++ w/src/ci/MEDfileCompatibility.c
@@ -71,7 +71,7 @@ MEDfileCompatibility(const char* const filename,
   _hversionMMR=10000*_hmajeur+100*_hmineur+_hrelease;
   /* ISCRUTE(_hversionMMR); */
   /* ISCRUTE(HDF_VERSION_NUM_REF); */
-  if ( (_hversionMMR >= HDF_VERSION_NUM_REF) && (_hmineur == HDF_VERSION_MINOR_REF) ) *hdfok = MED_TRUE;
+  if (_hversionMMR >= HDF_VERSION_NUM_REF) *hdfok = MED_TRUE;
 
   /* TODO : Vérifier si la version mineure HDF du fichier est supérieur 
      à la version mineure de la bibliothèque HDF utilisée  */
diff --git c/src/hdfi/_MEDfileCreate.c w/src/hdfi/_MEDfileCreate.c
index 34c75cc..66073c1 100644
--- c/src/hdfi/_MEDfileCreate.c
+++ w/src/hdfi/_MEDfileCreate.c
@@ -84,7 +84,7 @@ med_idt _MEDfileCreate(const char * const filename, const med_access_mode access
    * En HDF5-1.10.0p1 cela n'a aucun effet ! 
    * Un test autoconf permet de fixer un intervalle de version HDF à MED.
    */
-#if H5_VERS_MINOR > 10
+#if H5_VERS_MINOR > 12
 #error "Don't forget to change the compatibility version of the library !"
 #endif
    
diff --git c/src/hdfi/_MEDfileOpen.c w/src/hdfi/_MEDfileOpen.c
index 7d0b798..6a7de9a 100644
--- c/src/hdfi/_MEDfileOpen.c
+++ w/src/hdfi/_MEDfileOpen.c
@@ -72,7 +72,7 @@ med_idt _MEDfileOpen(const char * const filename,const med_access_mode accessmod
 
    •   The creation order tracking property, H5P_CRT_ORDER_TRACKED, has been set in the group creation property list (see H5Pset_link_creation_order). 
   */
-#if H5_VERS_MINOR > 10
+#if H5_VERS_MINOR > 12
 #error "Don't forget to change the compatibility version of the library !"
 #endif
 /* L'avantage de bloquer le modèle interne HDF5 
diff --git c/src/hdfi/_MEDmemFileOpen.c w/src/hdfi/_MEDmemFileOpen.c
index 9449cda..a3f4adc 100644
--- c/src/hdfi/_MEDmemFileOpen.c
+++ w/src/hdfi/_MEDmemFileOpen.c
@@ -434,7 +434,7 @@ med_idt _MEDmemFileOpen(const char * const filename, med_memfile * const memfile
     goto ERROR;
   }
 
-#if H5_VERS_MINOR > 10
+#if H5_VERS_MINOR > 12
 #error "Don't forget to change the compatibility version of the library !"
 #endif
   if ( H5Pset_libver_bounds( _fapl, H5F_LIBVER_18, H5F_LIBVER_18) ) {
diff --git c/src/hdfi/_MEDparFileCreate.c w/src/hdfi/_MEDparFileCreate.c
index c6d9f44..b3b2a41 100644
--- c/src/hdfi/_MEDparFileCreate.c
+++ w/src/hdfi/_MEDparFileCreate.c
@@ -64,7 +64,7 @@ med_idt _MEDparFileCreate(const char * const filename, const med_access_mode acc
    * En HDF5-1.10.0p1 cela n'a aucun effet ! 
    * Un test autoconf permet de fixer un intervalle de version HDF à MED.
    */
-#if H5_VERS_MINOR > 10
+#if H5_VERS_MINOR > 12
 #error "Don't forget to change the compatibility version of the library !"
 #endif
    
diff --git c/src/hdfi/_MEDparFileOpen.c w/src/hdfi/_MEDparFileOpen.c
index 0100729..dfad95c 100644
--- c/src/hdfi/_MEDparFileOpen.c
+++ w/src/hdfi/_MEDparFileOpen.c
@@ -55,7 +55,7 @@ med_idt _MEDparFileOpen(const char * const filename,const med_access_mode access
     MED_ERR_(_fid,MED_ERR_INIT,MED_ERR_PROPERTY,MED_ERR_PARALLEL_MSG);
     goto ERROR;
   }
-#if H5_VERS_MINOR > 10
+#if H5_VERS_MINOR > 12
 #error "Don't forget to change the compatibility version of the library !"
 #endif
   if ( H5Pset_libver_bounds( _fapl, H5F_LIBVER_18, H5F_LIBVER_18 ) ) {
--- med-4.1.0/src/ci/MEDfileCompatibility.c.old	2021-08-20 09:17:12.164865005 -0500
+++ med-4.1.0/src/ci/MEDfileCompatibility.c	2021-08-20 09:18:03.598103827 -0500
@@ -113,7 +113,7 @@
 #if MED_NUM_MAJEUR != 4
 #error "Don't forget to update the test version here when you change the major version of the library !"
 #endif
-#if H5_VERS_MINOR > 10
+#if H5_VERS_MINOR > 12
 #error "Don't forget to check the compatibility version of the library, depending on the internal hdf model choice !"
 #error "Cf. _MEDfileCreate ..."
 #endif
--- med-4.1.0/config/cmake_files/deprecated/FindHDF5.cmake.old	2021-08-20 14:08:51.264273175 -0500
+++ med-4.1.0/config/cmake_files/deprecated/FindHDF5.cmake	2021-08-20 14:09:51.845756742 -0500
@@ -109,7 +109,7 @@
 	SET(HDF5_INCLUDE_DIRS ${HDF5_INCLUDE_DIR})
       ENDIF(${HDF5_INCLUDE_DIR} STREQUAL /usr/include)
     ENDIF(HDF5_ROOT_USER)
-    SET(HDF5_DEFINITIONS "-DH5_USE_16_API -D_HDF5USEDLL_")
+    SET(HDF5_DEFINITIONS "-DH5_USE_16_API -DH5_USE_18_API -D_HDF5USEDLL_")
     MESSAGE(STATUS "${HDF5_INCLUDE_TO_FIND} found in ${HDF5_INCLUDE_DIR}")
   ELSE(HDF5_INCLUDE_DIR)
     SET(HDF5_STATUS 0)
--- med-4.1.0/config/cmake_files/medMacros.cmake.old	2021-08-20 14:08:51.268273272 -0500
+++ med-4.1.0/config/cmake_files/medMacros.cmake	2021-08-20 14:10:21.854491625 -0500
@@ -453,7 +453,7 @@
     ##
     ##
 
-    ADD_DEFINITIONS(-DH5_USE_16_API)  
+    ADD_DEFINITIONS(-DH5_USE_16_API -DH5_USE_18_API)  
     IF(WIN32 AND MEDFILE_BUILD_SHARED_LIBS)
       ADD_DEFINITIONS(-D_HDF5USEDLL_ -DH5_BUILT_AS_DYNAMIC_LIB=1)   
     ENDIF()
--- med-4.1.0/config/med_check_hdf5.m4.old	2021-08-20 14:08:51.268273272 -0500
+++ med-4.1.0/config/med_check_hdf5.m4	2021-08-20 14:10:42.190989648 -0500
@@ -167,7 +167,7 @@
 
 
 #      AC_DEFINE(H5_USE_16_API,[],[Using HDF5-1.6 API compatibility with HDF5 1.8 libraries])
-      HDF5_CPPFLAGS="-DH5_USE_16_API"
+      HDF5_CPPFLAGS="-DH5_USE_16_API -DH5_USE_18_API"
       HDF5_CPPFLAGS="$HDF5_CPPFLAGS -I$hdf5include"
       HDF5_LDFLAGS="-L$hdf5lib"
       LDFLAGS="$LDFLAGS_save"
--- med-4.1.0/configure.old	2021-08-20 14:08:51.268273272 -0500
+++ med-4.1.0/configure	2021-08-20 14:11:04.003523790 -0500
@@ -7786,7 +7786,7 @@
 
 
 #      AC_DEFINE(H5_USE_16_API,[],[Using HDF5-1.6 API compatibility with HDF5 1.8 libraries])
-      HDF5_CPPFLAGS="-DH5_USE_16_API"
+      HDF5_CPPFLAGS="-DH5_USE_16_API -DH5_USE_18_API"
       HDF5_CPPFLAGS="$HDF5_CPPFLAGS -I$hdf5include"
       HDF5_LDFLAGS="-L$hdf5lib"
       LDFLAGS="$LDFLAGS_save"