--- a/cmake/OpenCVDetectPython.cmake	
+++ a/cmake/OpenCVDetectPython.cmake	
@@ -186,7 +186,7 @@ if(NOT ${found})
         else() #debian based assumed, install to the dist-packages.
           set(_packages_path "python${_version_major_minor}/dist-packages")
         endif()
-        set(_packages_path "lib/${_packages_path}")
+        set(_packages_path "lib64/${_packages_path}")
       elseif(CMAKE_HOST_WIN32)
         get_filename_component(_path "${_executable}" PATH)
         file(TO_CMAKE_PATH "${_path}" _path)