--- a/dev-util/apitrace/apitrace-8.0.ebuild	
+++ a/dev-util/apitrace/apitrace-8.0.ebuild	
@@ -18,7 +18,7 @@ IUSE="+cli egl qt5 system-snappy"
 REQUIRED_USE="${PYTHON_REQUIRED_USE}"
 
 DEPEND="${PYTHON_DEPS}
-	app-arch/brotli:=
+	app-arch/brotli:=[${MULTILIB_USEDEP}]
 	media-libs/libpng:0=
 	media-libs/mesa[egl?,${MULTILIB_USEDEP}]
 	sys-libs/zlib[${MULTILIB_USEDEP}]