diff --git a/tool/util.c b/tool/util.c
index de6b071..5b299ca 100644
--- a/tool/util.c
+++ b/tool/util.c
@@ -38,6 +38,7 @@
 #endif
 
 #include "openssl-compat.h"
+#include <openssl/bn.h>
 #include <openssl/evp.h>
 #include <openssl/x509.h>
 #include <openssl/rsa.h>
diff --git a/tool/yubico-piv-tool.c b/tool/yubico-piv-tool.c
index 89daa79..9d6c7e1 100644
--- a/tool/yubico-piv-tool.c
+++ b/tool/yubico-piv-tool.c
@@ -43,10 +43,12 @@
 #endif
 
 #include "openssl-compat.h"
+#include <openssl/bn.h>
 #include <openssl/des.h>
 #include <openssl/pem.h>
 #include <openssl/pkcs12.h>
 #include <openssl/rand.h>
+#include <openssl/rsa.h>
 
 #include "cmdline.h"
 #include "util.h"
@@ -859,11 +861,19 @@ static bool selfsign_certificate(ykpiv_state *state, enum enum_key_format key_fo
     fprintf(stderr, "Failed to set certificate serial.\n");
     goto selfsign_out;
   }
+#if OPENSSL_VERSION_NUMBER < 0x10100000L
   if(!X509_gmtime_adj(X509_get_notBefore(x509), 0)) {
+#else
+  if(!X509_gmtime_adj(X509_getm_notBefore(x509), 0)) {
+#endif
     fprintf(stderr, "Failed to set certificate notBefore.\n");
     goto selfsign_out;
   }
+#if OPENSSL_VERSION_NUMBER < 0x10100000L
   if(!X509_gmtime_adj(X509_get_notAfter(x509), 60L * 60L * 24L * validDays)) {
+#else
+  if(!X509_gmtime_adj(X509_getm_notAfter(x509), 60L * 60L * 24L * validDays)) {
+#endif
     fprintf(stderr, "Failed to set certificate notAfter.\n");
     goto selfsign_out;
   }
@@ -1232,7 +1242,7 @@ static void print_cert_info(ykpiv_state *state, enum enum_slot slot, const EVP_M
 
   if(*ptr++ == 0x70) {
     unsigned int md_len = sizeof(data);
-    ASN1_TIME *not_before, *not_after;
+    const ASN1_TIME *not_before, *not_after;
 
     ptr += get_length(ptr, &cert_len);
     x509 = X509_new();
@@ -1290,13 +1300,21 @@ static void print_cert_info(ykpiv_state *state, enum enum_slot slot, const EVP_M
     dump_data(data, md_len, output, false, format_arg_hex);
 
     bio = BIO_new_fp(output, BIO_NOCLOSE | BIO_FP_TEXT);
+#if OPENSSL_VERSION_NUMBER < 0x10100000L
     not_before = X509_get_notBefore(x509);
+#else
+    not_before = X509_get0_notBefore(x509);
+#endif
     if(not_before) {
       fprintf(output, "\tNot Before:\t");
       ASN1_TIME_print(bio, not_before);
       fprintf(output, "\n");
     }
+#if OPENSSL_VERSION_NUMBER < 0x10100000L
     not_after = X509_get_notAfter(x509);
+#else
+    not_after = X509_get0_notAfter(x509);
+#endif
     if(not_after) {
       fprintf(output, "\tNot After:\t");
       ASN1_TIME_print(bio, not_after);
@@ -1941,7 +1959,9 @@ int main(int argc, char *argv[]) {
 
 
   /* openssl setup.. */
+#if OPENSSL_VERSION_NUMBER < 0x10100000L
   OpenSSL_add_all_algorithms();
+#endif
 
 
   for(i = 0; i < args_info.action_given; i++) {
@@ -2182,6 +2202,8 @@ int main(int argc, char *argv[]) {
   }
 
   ykpiv_done(state);
+#if OPENSSL_VERSION_NUMBER < 0x10100000L
   EVP_cleanup();
+#endif
   return ret;
 }
diff --git a/ykcs11/openssl_types.h b/ykcs11/openssl_types.h
index 307f746..08170fc 100644
--- a/ykcs11/openssl_types.h
+++ b/ykcs11/openssl_types.h
@@ -31,6 +31,7 @@
 #ifndef OPENSSL_TYPES_H
 #define OPENSSL_TYPES_H
 
+#include <openssl/bn.h>
 #include <openssl/x509.h>
 #include <openssl/evp.h>
 #include <openssl/rsa.h>
diff --git a/ykcs11/openssl_utils.c b/ykcs11/openssl_utils.c
index 68fb29a..172cd79 100644
--- a/ykcs11/openssl_utils.c
+++ b/ykcs11/openssl_utils.c
@@ -35,6 +35,11 @@
 #include "debug.h"
 #include <string.h>
 
+#if OPENSSL_VERSION_NUMBER >= 0x10100000L
+# define X509_set_notBefore X509_set1_notBefore
+# define X509_set_notAfter X509_set1_notAfter
+#endif
+
 CK_RV do_store_cert(CK_BYTE_PTR data, CK_ULONG len, X509 **cert) {
 
   const unsigned char *p = data; // Mandatory temp variable required by OpenSSL
@@ -580,7 +585,9 @@ CK_RV do_pkcs_pss(ykcs11_rsa_key_t *key, CK_BYTE_PTR in, CK_ULONG in_len,
           int nid, CK_BYTE_PTR out, CK_ULONG_PTR out_len) {
   unsigned char em[RSA_size(key)];
 
+#if OPENSSL_VERSION_NUMBER < 0x10100000L
   OpenSSL_add_all_digests();
+#endif
 
   DBG("Apply PSS padding to %lu bytes and get %d", in_len, RSA_size(key));
 
@@ -590,14 +597,18 @@ CK_RV do_pkcs_pss(ykcs11_rsa_key_t *key, CK_BYTE_PTR in, CK_ULONG in_len,
 
   // In case of raw PSS (no hash) this function will fail because OpenSSL requires an MD
   if (RSA_padding_add_PKCS1_PSS(key, em, out, EVP_get_digestbynid(nid), -2) == 0) {
+#if OPENSSL_VERSION_NUMBER < 0x10100000L
     EVP_cleanup();
+#endif
     return CKR_FUNCTION_FAILED;
   }
 
   memcpy(out, em, sizeof(em));
   *out_len = (CK_ULONG) sizeof(em);
 
+#if OPENSSL_VERSION_NUMBER < 0x10100000L
   EVP_cleanup();
+#endif
 
   return CKR_OK;
 }