1. Create a MySQL database if you haven't already one. 2. Navigate to your gallery. Example: if you uploaded in a subfolder named "zenphoto" navigate to www.yoursite.org/zenphoto/. Setup.php will run. (If it somehow does not, please navigate directly to www.yoursite.org/zenphoto/zp-core/setup.php) 3. Enter the MySQL credentials and make sure everything checks out. 4. Then click GO! 5. ENJOY!