--- m2crypto-0.20.2.ebuild-old	2010-10-20 18:55:42.466883374 +0200
+++ m2crypto-0.20.2.ebuild	2010-10-20 18:55:35.330781498 +0200
@@ -35,6 +35,7 @@
 src_prepare() {
 	distutils_src_prepare
 	epatch "${FILESDIR}/${P}-openssl-1.0.0.patch"
+    sed "s_self.openssl = '/usr'_self.openssl = '${EPREFIX}/usr'_g" -i setup.py 
 }
 
 src_compile() {