--- python.eclass
+++ python.eclass
@@ -774,6 +774,8 @@
 import sys
 
 EPYTHON_re = re.compile(r"^python(\d+\.\d+)$")
+python_shebang_re = re.compile(r"^#!.*python")
+python_verification_output_re = re.compile("^GENTOO_PYTHON_TARGET_SCRIPT_PATH supported\n$")
 
 EOF
 		if [[ "$?" != "0" ]]; then
@@ -798,16 +800,16 @@
 		sys.stderr.write("Execution of 'eselect python show${eselect_python_option:+ }${eselect_python_option}' failed\n")
 		sys.exit(1)
 
-	eselect_output = eselect_process.stdout.read()
-	if not isinstance(eselect_output, str):
+	EPYTHON = eselect_process.stdout.read().rstrip("\n")
+	if not isinstance(EPYTHON, str):
 		# Python 3
-		eselect_output = eselect_output.decode()
+		EPYTHON = EPYTHON.decode()
 
-	EPYTHON_matched = EPYTHON_re.match(eselect_output)
+	EPYTHON_matched = EPYTHON_re.match(EPYTHON)
 	if EPYTHON_matched:
 		PYTHON_ABI = EPYTHON_matched.group(1)
 	else:
-		sys.stderr.write("'eselect python show${eselect_python_option:+ }${eselect_python_option}' printed unrecognized value '%s" % eselect_output)
+		sys.stderr.write("'eselect python show${eselect_python_option:+ }${eselect_python_option}' printed unrecognized value '%s" % EPYTHON)
 		sys.exit(1)
 EOF
 			if [[ "$?" != "0" ]]; then
@@ -823,16 +825,16 @@
 	sys.stderr.write("Execution of 'eselect python show${eselect_python_option:+ }${eselect_python_option}' failed\n")
 	sys.exit(1)
 
-eselect_output = eselect_process.stdout.read()
-if not isinstance(eselect_output, str):
+EPYTHON = eselect_process.stdout.read().rstrip("\n")
+if not isinstance(EPYTHON, str):
 	# Python 3
-	eselect_output = eselect_output.decode()
+	EPYTHON = EPYTHON.decode()
 
-EPYTHON_matched = EPYTHON_re.match(eselect_output)
+EPYTHON_matched = EPYTHON_re.match(EPYTHON)
 if EPYTHON_matched:
 	PYTHON_ABI = EPYTHON_matched.group(1)
 else:
-	sys.stderr.write("'eselect python show${eselect_python_option:+ }${eselect_python_option}' printed unrecognized value '%s" % eselect_output)
+	sys.stderr.write("'eselect python show${eselect_python_option:+ }${eselect_python_option}' printed unrecognized value '%s" % EPYTHON)
 	sys.exit(1)
 EOF
 			if [[ "$?" != "0" ]]; then
@@ -841,13 +843,47 @@
 		fi
 		cat << EOF >> "${file}"
 
-os.environ["PYTHON_SCRIPT_NAME"] = sys.argv[0]
-target_executable = "%s-%s" % (os.path.realpath(sys.argv[0]), PYTHON_ABI)
-if not os.path.exists(target_executable):
-	sys.stderr.write("'%s' does not exist\n" % target_executable)
+wrapper_script_path = os.path.realpath(sys.argv[0])
+target_executable_path = "%s-%s" % (wrapper_script_path, PYTHON_ABI)
+os.environ["GENTOO_PYTHON_WRAPPER_SCRIPT_PATH"] = sys.argv[0]
+os.environ["GENTOO_PYTHON_TARGET_SCRIPT_PATH"] = target_executable_path
+if not os.path.exists(target_executable_path):
+	sys.stderr.write("'%s' does not exist\n" % target_executable_path)
 	sys.exit(1)
 
-os.execv(target_executable, sys.argv)
+target_executable = open(target_executable_path, "rb")
+target_executable_first_line = target_executable.readline()
+if not isinstance(target_executable_first_line, str):
+	# Python 3
+	target_executable_first_line = target_executable_first_line.decode("utf_8", "replace")
+
+python_shebang_matched = python_shebang_re.match(target_executable_first_line)
+target_executable.close()
+
+if python_shebang_matched:
+	try:
+		python_interpreter_path = "${EPREFIX}/usr/bin/%s" % EPYTHON
+		os.environ["GENTOO_PYTHON_TARGET_SCRIPT_PATH_VERIFICATION"] = "1"
+		python_verification_process = subprocess.Popen([python_interpreter_path, "-c", "pass"], stdout=subprocess.PIPE)
+		del os.environ["GENTOO_PYTHON_TARGET_SCRIPT_PATH_VERIFICATION"]
+		if python_verification_process.wait() != 0:
+			raise ValueError
+
+		python_verification_output = python_verification_process.stdout.read()
+		if not isinstance(python_verification_output, str):
+			# Python 3
+			python_verification_output = python_verification_output.decode()
+
+		if not python_verification_output_re.match(python_verification_output):
+			raise ValueError
+
+		os.execv(python_interpreter_path, [python_interpreter_path] + sys.argv)
+	except:
+		pass
+	if "GENTOO_PYTHON_TARGET_SCRIPT_PATH_VERIFICATION" in os.environ:
+		del os.environ["GENTOO_PYTHON_TARGET_SCRIPT_PATH_VERIFICATION"]
+
+os.execv(target_executable_path, sys.argv)
 EOF
 		if [[ "$?" != "0" ]]; then
 			die "${FUNCNAME}(): Generation of '$1' failed"