--- a/sys-libs/libomp/libomp-17.0.6.ebuild	
+++ a/sys-libs/libomp/libomp-17.0.6.ebuild	
@@ -113,8 +113,6 @@ multilib_src_configure() {
 		-DLIBOMP_INSTALL_ALIASES=OFF
 		# disable unnecessary hack copying stuff back to srcdir
 		-DLIBOMP_COPY_EXPORTS=OFF
-		# prevent trying to access the GPU
-		-DLIBOMPTARGET_AMDGPU_ARCH=LIBOMPTARGET_AMDGPU_ARCH-NOTFOUND
 	)
 
 	if [[ ${build_omptarget} == ON ]]; then
@@ -122,6 +120,10 @@ multilib_src_configure() {
 			mycmakeargs+=(
 				-DLIBOMPTARGET_BUILD_AMDGPU_PLUGIN=$(usex llvm_targets_AMDGPU)
 				-DLIBOMPTARGET_BUILD_CUDA_PLUGIN=$(usex llvm_targets_NVPTX)
+
+				# prevent trying to access the GPU
+				-DLIBOMPTARGET_AMDGPU_ARCH=LIBOMPTARGET_AMDGPU_ARCH-NOTFOUND
+				-DLIBOMPTARGET_NVPTX_ARCH=LIBOMPTARGET_NVPTX_ARCH-NOTFOUND
 			)
 		else
 			mycmakeargs+=(