For the second time in few weeks, I helped out someone on the forums who had installed gnome, had cups installed, but didn't have System->Administration->Printing, i.e. gnome-cups-manager, to control their printers. This package should either be a dependency of the gnome meta-package controlled by the cups USE flag, or it should be a dependency of cups if the gnome USE flag is set. Having a modern desktop environment with no easy way to setup/control printers is not a good situation. Poking around the ebuilds, I see that nautilus used to have a cups USE flag (now commented out) so this isn't a new idea. What makes solving this particular problem even harder for people is that there is a gnome-print package also available. It's for gnome-1.x apps and therefore useless for current-day gnome, but people searching for a package to manage their printers under gnome see that and think they've found the answer -- until it doesn't work.
gnome-2.16.0 has a cups USE flag that pulls in gnome-cups-manager. cups is on by default in most profiles.